Women seeking motherhood

When pregnancy does not come

The lack of a pregnancy after a long period of unprotected intercourses configures a problem of couple infertility. From a statistical point of view the chances that the lower fertility is of male or female origin are substantially equal and in almost half the cases both coexist. Yet we still live an era of frequent aggressive diagnosis and therapy on the female side, partly the result of cultural heritage, while a male problem is sometimes considered as a last resort. So, the first thing a woman unable to obtain pregnancies must do is convince her doctor and her partner to immediately face also the other side of the problem.

On the female side, the doctor will check if the patient ovulates regularly if there are endocrine or adnexal problems and will possibly investigate chromosomal and / or genetic status. These tests might highlight a problem suitable for surgical or medical therapy. In other cases, they will individuate some concomitant conditions having an adverse effect on fertility, typical examples are the polycystic ovary syndrome and endometriosis. Even if these conditions are not always “curable”, the awareness of the problem will direct to the most appropriate treatment strategies.

When ovulation is impaired

Partial ovulatory irregularity and occasional anovulation are almost normal and do not necessarily imply a reduced fertility. The doctor will be able to easily understand the extent of the fertility problem by monitoring several cycles with the aid of hormonal tests and / or ultrasounds. Te reproductive age of women older than 35 years and of all suspected cases should be investigated with greater care by the antral follicles count and / or by the dosage of the anti-Mullerian hormone (AMH).

The cycle irregularities physiologically tend to increase with reproductive ageing and may be an alarm bell suggesting that fertility is declining. In contrast, the same irregularities are also common in very young women, often within a polycystic ovary syndrome. Most of these situations can be improved with the aid of medical therapies. Nutritional supplements with antioxidant effects may contribute effectively and sometimes are decisive. Women who suffer from serious disorders of ovulation may instead require a more complex diagnostic and therapeutic pathway and sometimes must undergo to ART.

When you take antioxidants

Even in the absence of known problems, an antioxidant support to the development of the oocyte, which lasts about three months, is always advisable. But, it is necessary to avoid aggressive interventions with substances with pharmacological activity. The so-called direct antioxidants such as e.g. vitamins C, E and A, coenzyme Q, selenium and the like, especially at high doses, perturbed the cellular redox balance and are likely to cause the opposite imbalance, leading to even more severe consequences.

All cells and first of all the gametes need a perfect osx-redox balance that can be achieved only by a normalization of cellular activity. While a balanced diet provides all the substances (several hundred) that work together to balance cell in quantities and combinations selected by evolution, the intake of antioxidants in the form of supplements, even more if highly active, only serves to stress in reductive sense the specific chemical reactions in which each of these substances are involved. This means blocking these responses them for the opposite imbalance. There are no magic remedies or special substances that correct all the biochemical changes.

Effective support of cellular redox equilibrium can instead be achieved by providing the cell, rather than pre-formed antioxidants, the substances that the same cell needs to produce antioxidants on its own, i.e. when and where they are needed, in the right quantities and until they are required.

Condensyl and Procrelia are indeed based on the principle of the indirect antioxidant support, i.e. a pure nutritional intervention to sustain an efficient metabolism, and for the first time significant clinical effects on fertility have been demonstrated (Cornet et al. 2015).

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